The Heart is created, hosted, and narrated by Kaitlin Prest, who frequently appears as a subject within her own episodes rather than staying behind the microphone. The show is produced by Prest's company Mermaid Palace and released through the Radiotopia podcast network. Its most recent run centers on the 'NO' series, in which Prest revisits a specific consent violation involving a longtime friend referred to as Jay, listens back to archival tape of earlier encounters, brings in panelists such as Phoebe Wang, and eventually confronts Jay directly, closing with reflections on bell hooks and restorative justice. Running alongside this is a set of Gaza monologue episodes made in partnership with Ashtar Theater's Gaza Monologues project, built from testimony recorded with Palestinian evacuees, including siblings Ahmed, Hamza, and Tarneem Jabir, describing displacement to Cairo and interrupted medical and dental studies. A separate serialized entry, 'The Shadows,' is a semi-autobiographical audio drama about a long-term relationship, using actors alongside interviews with Prest's own parents. Formats vary episode to episode: some are solo narrated essays, others are structured interviews or multi-person panel conversations, and several use scripted reenactment with actors standing in for real people, with the reenactment disclosed to the listener. Guests tend to be either people directly tied to the personal stories being told — friends, exes, family — or subjects of the documentary strands, such as Palestinian students and theater artists. Episodes commonly close with production credits for Mermaid Palace and Radiotopia and, in the Gaza episodes, appeals to support named individuals through fundraisers. Production leans on layered narration, sound design, and cross-referenced archival audio rather than a straightforward talk format. Listeners drawn to first-person audio documentary about consent, intimate relationships, and war testimony are the core audience.