Active Mom Podcast: Pregnancy, Postpartum, Perimenopause, Menopause & Beyond · Carrie

Regenerative Medicine for Pelvic Organ Prolapse: What Women Should Know About PRP — with DR. IMRAN SIDDIQUI

·42 min·3 clips

Dr. Siddiqui reveals how platelets trigger the body's natural healing response with growth factors.

Dr. Keri Pagliano hosts Dr. Imran Siddiqui, a musculoskeletal physician specializing in imaging and regenerative treatments. This episode focuses on platelet-rich plasma therapy for pelvic organ prolapse and related conditions. Dr. Siddiqui explains PRP's foundational principle in the body's natural healing process. He describes how bleeding from a cut introduces platelets that bind to damaged tissue and release growth factors. PRP therapy concentrates a patient's own platelets from drawn blood via centrifugation to create an injectable solution. Dr. Siddiqui initially applied PRP in musculoskeletal contexts like tendon injuries before expanding to pelvic floor applications. The discussion covers using PRP specifically for pelvic organ prolapse, addressing connective tissue and ligament support. Dr. Siddiqui details the procedural steps, from blood draw to ultrasound-guided injection into targeted pelvic structures. He contrasts PRP with other proliferative therapies like prolotherapy, emphasizing the concentrated growth factors in PRP. A key insight is the proposed mechanism where growth factors may stimulate tissue repair and strengthening in pelvic support systems. Dr. Siddiqui addresses the current evidence base, noting growing research interest but acknowledging the need for more large-scale studies in pelvic health. He shares clinical observations on patient outcomes and recovery timelines post-procedure. The conversation explores candidacy for PRP, considering factors like prolapse severity and individual health status. Dr. Pagliano inquires about integrating PRP with pelvic floor physical therapy for a comprehensive approach. Dr. Siddiqui emphasizes the outpatient nature of the procedure and its generally well-tolerated profile. The tone is educational and conversational, blending medical explanation with practical clinical perspective. It is an interview-style dialogue aimed at demystifying a specialized treatment. Listeners interested in non-surgical options for pelvic organ prolapse would find this episode highly relevant. Those seeking solely exercise-based management or definitive surgical discussions might find the focus too narrow.

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