The Female Biohacker's Guide to Living to 150 | Ep76

March 31, 2025·1 hr 2 min·5 clips

Standard tea bags release microplastics into hot water, and those plastics have now been found in ovaries, placentas, and brain tissue.

Host Vishen Lakhiani, sitting in for regular host Megan Palmer, opens by introducing Kayla Barnes as a foremost female biohacking and longevity expert and founder of Live the Wellness Space. Kayla's chronological age is 34 but her biological age test results place her approximately 10 years younger. She explains that methylation tests measure biological age and that individual organ ages, including cardiovascular age, are now also measurable. She describes the concept of longevity escape velocity — the point at which therapies reverse biological age faster than aging accumulates — and says AI will play a major role. Kayla began her longevity focus as an entrepreneur who wanted the physical capacity to sustain intense work, starting with nutrition in college and deepening into biohacking over the past five years in preparation for opening her wellness clinic. She describes discovering elevated environmental toxin levels in her own labs and beginning to work on detox protocols. The conversation turns to microplastics, prompted by Kayla declining tea bags on set. She explains that plastic tea bags release microplastics when exposed to hot water and that microplastics have been found in every organ tested, including ovaries, placentas, and brain tissue. She describes her total toxic burden testing and how she detected a shift after the LA wildfires. Kayla's morning routine includes oil pulling, tongue scraping, flossing, red light therapy, PEMF mat use, breathwork, meditation, morning sunlight, and gym training. She describes taking her cardiovascular age from negative 6 to negative 11.5 years in six months using the Norwegian four-by-four VO2 max protocol and a Carol AI bike. She highlights that for women the recovery interval should extend to six minutes rather than four, based on guidance from Dr. Stacy Sims. Her workday incorporates PEMF, red light therapy for hair growth, intranasal red light, and a Nano-V device for protein folding. She does 40 hyperbaric oxygen sessions as a loading dose and then two to three maintenance sessions weekly. Vishen asks whether such a regimented life removes joy; Kayla argues that cultural conditioning equates harm with fun and that she finds joy in high energy and strong biomarkers. She addresses female-specific longevity advice, noting that most biohacking guidance comes from men and that women's 28-to-30-day hormonal cycle requires different protocols for cold therapy, fasting, exercise intensity, and nutrition. She recommends cold therapy only during the follicular phase and extending recovery periods during VO2 max training. Her entry-level advice for women: sleep before 10 PM, walk 10,000 steps, and eliminate processed foods.

As heard by us

A brisk longevity discussion that turns aging into a daily discipline.

This episode treats longevity as a daily discipline, not a slogan. Vishen Lakhiani talks with Kayla Barnes about biological age, the idea that internal age can differ from chronological age, and the push to slow biological aging as much as possible.

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Why you'd press play

An ambitious longevity chat with Kayla Barnes that turns biological age and optimization habits into something you can actually picture using.

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