Latent Space: The AI Engineer Podcast · Latent.Space

🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery

·1 hr 21 min·5 clips

AlphaFold 3 was kept internal, cutting off access for scientists and sparking the creation of open-source Boltz.

Gabriela Corso and Jeremy Volvin discuss their journey from MIT PhDs to founding Boltz, an open-source initiative to democratize protein structure prediction. They cover the impact of AlphaFold 2 and 3, the challenges of building Boltz 1 with limited compute, and their latest models for protein and small molecule design, validated across multiple labs.

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